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Agents can be used inside the consolidation, yet not, somebody may experience higher side effects. Methotrexate is an essential and you may useful DMARD which can be always the first therapy. A blended means with methotrexate and you can biologics improves ACR50, HAQ ratings and you will RA remission costs. Triple medication composed of methotrexate, sulfasalazine and you can hydroxychloroquine can also efficiently control state interest. Adverse effects will likely be monitored regularly that have toxicity as well as gastrointestinal, hematologic, pulmonary, and you may hepatic.
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